Scientist, Sequencing Cover Letter

I would like to submit my application for the scientist, sequencing opening. Please accept this letter and the attached resume.

In my previous role, I was responsible for technical support to the development of diagnostic genetic sequencing methods using Sanger and NGS technologies for identification of influenza viruses.

Please consider my experience and qualifications for this position:

• Experienced with statistical methods for large dataset analysis (i.e., JMP)
• Presents findings or comprehensive project status reviews at internal/external seminars/meetings
• Establishes and maintains productive relationship with personnel in development
• Designs, plans and executes feasibility studies independently, accurately and consistently records experimental methods, materials and results in electronic laboratory notebooks
• Participates in project planning, process updates, and critical decision making
• Serves as a resource to other departments (e.g., Manufacturing/Operations, Quality, Marketing, Regulatory Affairs, Clinical Studies, and International Technical Services), provides timely response and follow-ups
• Experience with operating and programming liquid handling systems is preferred
• Stand or sit for extended periods of time, potentially performing repetitive motion

Please consider me for the scientist, sequencing opportunity. I am including my resume that lists my qualifications and experience.

In my previous role, I was responsible for translational oncology expertise to curation team; must be able to interpret complex genomic data from various technologies including next-generation sequencing.

Please consider my experience and qualifications for this position:

• Proven track record of assay development for library preparation and target enrichment (preferably capture by hybridization methods)
• Excellent understanding of the underlying technical principles of next generation sequencing chemistries and workflows and data analysis
• Demonstrated expertise in optimizing complex chemical/biochemical processes, particularly in relationship to utilization of modified substrates
• Experience building model in complex arenas, including recent relevant experience
• Experience with Algorithms development / Scientific computing
• A background in DNA sequencing technologies, bioinformatics, genetics, biology
• Strong statistical background, previous industry experience, familiarity with common bioinformatics tools, experience with high performance computing, understanding of assay design, experience working in cancer biology or human genetics or metagenomics, experience with clinical testing, are all highly advantageous
• Knowledge of CLIA compliance and regulatory guidelines

In response to your job posting for scientist, sequencing, I am including this letter and my resume for your review.

In the previous role, I was responsible for basic bioinformatics analysis and quality control for NGS datasets.

Please consider my qualifications and experience:

• Work with potentially toxic, flammable, and corrosive chemicals, in addition to biologic agents
• May be asked to work weekend, irregular, or overtime hours
• Exposure to potentially infectious clinical specimens in a biological safety level laboratory environment
• Familiarity with basic data management, processing, analysis, and reproducible research best practices
• Should thrive in a highly interactive, fast-paced and dynamic team environment
• Able to work independently for the direct responsibilities, with a team for the project transition points and with senior scientists for research
• Minimum of a BSc in a scientific discipline
• Proven experience of working with lab automation, including optimisation and troubleshooting

Please consider me for the scientist, sequencing opportunity. I am including my resume that lists my qualifications and experience.

In the previous role, I was responsible for information to customers regarding applications and related products for the NGS systems, including kits, reagents, Bioinformatics and ancillary devices.

My experience is an excellent fit for the list of requirements in this job:

• Experience of programming automated liquid handling systems
• Experience designing and troubleshooting sequencing assays (small and large targets, high GC areas)
• Experience evaluating and assembling sequencing data
• BS or MS in molecular biology, biochemistry, chemical engineering or a related field
• Demonstrated proficiency with basic molecular biology techniques (PCR, gel electrophoresis, DNA quantification, spectrophotometer use)
• Demonstrated proficiency with next generation sequencing systems (preferably Illumina)
• Experience with automation instruments (liquid handlers, plate readers, ) preferred, but not essential
• Experience with isothermal amplification methods

Please consider me for the scientist, sequencing opportunity. I am including my resume that lists my qualifications and experience.

In my previous role, I was responsible for nGS bioinformatics leadership and support to the NGS programme.

My experience is an excellent fit for the list of requirements in this job:

• Broad, expert-level knowledge of next generation sequencing assays for DNA and RNA, including both general nucleic acid biochemistry specific optimizations for different applications, sequencing platforms, and analytes
• Experience in assay design/optimization, documentation and operation of a CLIA compliant lab
• Understanding of the biology of human cell-free nucleic acids, single-cell analysis methods and cancer genomics
• Training and experience in molecular biology techniques, including DNA, RNA isolation and quantification, electrophoresis, spectrophotometry, PCR, real-time PCR, and DNA cloning techniques
• Knowledge of applicable complex scientific procedures and techniques
• Experience managing scientific teams and mentoring junior scientists
• Experience with high throughput methods and strategies
• In depth knowledge of and direct experience with a variety of NGS applications such as Whole Genome Sequencing, RNAseq, and target-enrichment sequencing